{"guid":"f9e115c1-6da6-5f35-b9b4-9f95f8e49e58","title":"Hacking the genome: how does it work, and should we?","subtitle":null,"slug":"mch2022-16-hacking-the-genome-how-does-it-work-and-should-we-","link":"https://program.mch2022.org/mch2022/talk/Y898KK/","description":"Building on the very well attended DNA presentations (\"DNA: The Code Of Life\") at SHA2017, this talk will cover:\n\n * A brief recap what DNA is and how it works\n   * It is surprisingly digital!\n * How reading DNA is within 'pro-sumer' reach now\n   * (I might bring a live demo for after the talk)\n * An overview of DNA editing technologies (offline, and online: on living organisms)\n    * Including the famous CRISPR-CAS, but also newer variants\n * How does such editing actually work in a lab?\n * The surprising lack of a definitive link between most DNA mutations and any effect\n * Could you hack your DNA? Will people start doing this?\n   * Should we try to stop them?\n * Wild speculation on what this might mean for the future\n\nThe goal of this presentation is to provide real non-hyped information on what DNA editing is and what it might achieve. And since we are hackers, I hope to explain how a hackerspace could start reading DNA right now with USB-powered hardware. And finally, since no hacker can resist tinkering: could you hack your own genome, or your cat's, or improve on your favorite plant?\n\nBuilding on the very well attended DNA presentations (\"DNA: The Code Of Life\") at SHA2017, this talk will cover:\n\n * A brief recap what DNA is and how it works\n   * It is surprisingly digital!\n * How reading DNA is within 'pro-sumer' reach now\n   * (I might bring a live demo for after the talk)\n * An overview of DNA editing technologies (offline, and online: on living organisms)\n    * Including the famous CRISPR-CAS, but also newer variants\n * How does such editing actually work in a lab?\n * The surprising lack of a definitive link between most DNA mutations and any effect\n * Could you hack your DNA? Will people start doing this?\n   * Should we try to stop them?\n * Wild speculation on what this might mean for the future\n\nThe goal of this presentation is to provide real non-hyped information on what DNA editing is and what it might achieve. And since we are hackers, I hope to explain how a hackerspace could start reading DNA right now with USB-powered hardware. And finally, since no hacker can resist tinkering: could you hack your own genome, or your cat's, or improve on your favorite plant?","original_language":"eng","persons":["bert hubert"],"tags":["mch2022","16","2022","MCH2022 Curated content"],"view_count":1435,"promoted":false,"date":"2022-07-22T20:40:00.000+02:00","release_date":"2022-07-23T00:00:00.000+02:00","updated_at":"2026-03-28T13:15:07.006+01:00","length":2947,"duration":2947,"thumb_url":"https://static.media.ccc.de/media/events/MCH2022/16-f9e115c1-6da6-5f35-b9b4-9f95f8e49e58.jpg","poster_url":"https://static.media.ccc.de/media/events/MCH2022/16-f9e115c1-6da6-5f35-b9b4-9f95f8e49e58_preview.jpg","timeline_url":"https://static.media.ccc.de/media/events/MCH2022/16-f9e115c1-6da6-5f35-b9b4-9f95f8e49e58.timeline.jpg","thumbnails_url":"https://static.media.ccc.de/media/events/MCH2022/16-f9e115c1-6da6-5f35-b9b4-9f95f8e49e58.thumbnails.vtt","frontend_link":"https://media.ccc.de/v/mch2022-16-hacking-the-genome-how-does-it-work-and-should-we-","url":"https://api.media.ccc.de/public/events/f9e115c1-6da6-5f35-b9b4-9f95f8e49e58","conference_title":"May Contain Hackers 2022","conference_url":"https://api.media.ccc.de/public/conferences/MCH2022","related":[],"recordings":[{"size":306,"length":2947,"mime_type":"video/webm","language":"eng","filename":"mch2022-16-eng-Hacking_the_genome_how_does_it_work_and_should_we_webm-hd.webm","state":"new","folder":"webm-hd","high_quality":true,"width":1920,"height":1080,"updated_at":"2022-07-23T12:45:26.995+02:00","recording_url":"https://cdn.media.ccc.de/events/MCH2022/webm-hd/mch2022-16-eng-Hacking_the_genome_how_does_it_work_and_should_we_webm-hd.webm","url":"https://api.media.ccc.de/public/recordings/60050","event_url":"https://api.media.ccc.de/public/events/f9e115c1-6da6-5f35-b9b4-9f95f8e49e58","conference_url":"https://api.media.ccc.de/public/conferences/MCH2022"},{"size":113,"length":2947,"mime_type":"video/mp4","language":"eng","filename":"mch2022-16-eng-Hacking_the_genome_how_does_it_work_and_should_we_sd.mp4","state":"new","folder":"h264-sd","high_quality":false,"width":720,"height":576,"updated_at":"2022-07-23T11:06:07.553+02:00","recording_url":"https://cdn.media.ccc.de/events/MCH2022/h264-sd/mch2022-16-eng-Hacking_the_genome_how_does_it_work_and_should_we_sd.mp4","url":"https://api.media.ccc.de/public/recordings/60034","event_url":"https://api.media.ccc.de/public/events/f9e115c1-6da6-5f35-b9b4-9f95f8e49e58","conference_url":"https://api.media.ccc.de/public/conferences/MCH2022"},{"size":114,"length":2947,"mime_type":"video/webm","language":"eng","filename":"mch2022-16-eng-Hacking_the_genome_how_does_it_work_and_should_we_webm-sd.webm","state":"new","folder":"webm-sd","high_quality":false,"width":720,"height":576,"updated_at":"2022-07-23T11:04:32.501+02:00","recording_url":"https://cdn.media.ccc.de/events/MCH2022/webm-sd/mch2022-16-eng-Hacking_the_genome_how_does_it_work_and_should_we_webm-sd.webm","url":"https://api.media.ccc.de/public/recordings/60033","event_url":"https://api.media.ccc.de/public/events/f9e115c1-6da6-5f35-b9b4-9f95f8e49e58","conference_url":"https://api.media.ccc.de/public/conferences/MCH2022"},{"size":44,"length":2947,"mime_type":"audio/mpeg","language":"eng","filename":"mch2022-16-eng-Hacking_the_genome_how_does_it_work_and_should_we_mp3.mp3","state":"new","folder":"mp3","high_quality":false,"width":0,"height":0,"updated_at":"2022-07-23T10:13:23.146+02:00","recording_url":"https://cdn.media.ccc.de/events/MCH2022/mp3/mch2022-16-eng-Hacking_the_genome_how_does_it_work_and_should_we_mp3.mp3","url":"https://api.media.ccc.de/public/recordings/60030","event_url":"https://api.media.ccc.de/public/events/f9e115c1-6da6-5f35-b9b4-9f95f8e49e58","conference_url":"https://api.media.ccc.de/public/conferences/MCH2022"},{"size":25,"length":2947,"mime_type":"audio/opus","language":"eng","filename":"mch2022-16-eng-Hacking_the_genome_how_does_it_work_and_should_we_opus.opus","state":"new","folder":"opus","high_quality":false,"width":0,"height":0,"updated_at":"2022-07-23T10:13:03.927+02:00","recording_url":"https://cdn.media.ccc.de/events/MCH2022/opus/mch2022-16-eng-Hacking_the_genome_how_does_it_work_and_should_we_opus.opus","url":"https://api.media.ccc.de/public/recordings/60029","event_url":"https://api.media.ccc.de/public/events/f9e115c1-6da6-5f35-b9b4-9f95f8e49e58","conference_url":"https://api.media.ccc.de/public/conferences/MCH2022"},{"size":368,"length":2947,"mime_type":"video/mp4","language":"eng","filename":"mch2022-16-eng-Hacking_the_genome_how_does_it_work_and_should_we_hd.mp4","state":"new","folder":"h264-hd","high_quality":true,"width":1920,"height":1080,"updated_at":"2022-07-23T01:13:38.578+02:00","recording_url":"https://cdn.media.ccc.de/events/MCH2022/h264-hd/mch2022-16-eng-Hacking_the_genome_how_does_it_work_and_should_we_hd.mp4","url":"https://api.media.ccc.de/public/recordings/60021","event_url":"https://api.media.ccc.de/public/events/f9e115c1-6da6-5f35-b9b4-9f95f8e49e58","conference_url":"https://api.media.ccc.de/public/conferences/MCH2022"}]}